Denamarin Advanced and Denamarin
Liver Health Support for Dogs

  • Denamarin Chewable Tablets
    DENAMARIN Chewable Tablets

    The #1 veterinarian recommended liver support brand

    Denamarin is a supplement for dogs containing S-Adenosylmethionine (SAMe) and silybin


    Available in a 30 count size and a 75 count size for dogs of all sizes

     

  • Group of Denamarin Tablet products
    DENAMARIN Tablets

    The #1 veterinarian recommended liver support brand

    Denamarin is a supplement for dogs and cats containing S-Adenosylmethionine (SAMe) and silybin


    Available in sizes for cats & small dogs

     

  • Group of Denamarin Advanced products
    DENAMARIN Advanced chewable tablets

    The #1 veterinarian recommended liver support brand

    Latest SAMe Innovation

    Optimal Liver Support

     

Source: Survey conducted among small animal veterinarians who recommended liver support brands.

Denamarin®
Liver Health Support for Cats

    Denamarin for Cats
    DENAMARIN Tablets

    The #1 veterinarian recommended liver support brand

    Denamarin is a supplement for dogs and cats containing S-Adenosylmethionine (SAMe) and silybin


    Available in enteric-coated tablets for cats

    For optimal absorption, tablets should be given on an empty stomach, at least one hour before feeding, as the presence of food decreases the absorption of S-Adenosylmethionine. For those owners who have difficulty administering tablets to their pets, Denamarin tablet(s) may be disguised in a small bite of food. Studies have shown that, in many cases, tablets or capsules given as a "dry swallow" do not pass into the stomach in cats but may become lodged in the esophagus. It is recommended for pet owners to administer 3-6 cc of water immediately following any tablet administration to speed passage of the tablet into the stomach. 1, 2 Denamarin for Cats and Small Dogs tablets are ideal for cats because of their small size. If the pet is to receive more than one tablet daily, the total number of tablets may be divided between morning and evening for ease of administration.


    Feline Denamarin Daily* Administration Guide

    Denamarin For Cats

    S-Adenosylmethionine 90 mg and Silybin-phosphatidylcholine complex (SPC) 31 mg, providing 9 mg of Silybin A+B

    Body Weight Body Weight Number of Tablets Per Day
    Up to 12 lbs Up to 5.5 kg 1
    Over 12 lbs Over 5.5 kg 1 Twice Daily

    *The number of tablets can be gradually reduced or increased at any time depending on the pet's needs.

    Many pets are maintained long-term on every-other-day or every-third-day administration.


    Storage

    Store in a cool dry place. Keep tablets in original blister pack until used. Tablets are sensitive to moisture and extreme heat.

  • Denamarin Advanced Cat Hard Tablets

    DENAMARIN® Advanced for Cats

    The #1 veterinarian recommended liver support brand

    Latest SAMe Innovation

    Optimal Liver Support for Cats

     

Source: Survey conducted among small animal veterinarians who recommended liver support brands.

ABOUT
DENAMARIN

How does Denamarin ® work?

When liver function is compromised, the exact cause can often be difficult to determine. Supporting the liver, regardless of the cause, is essential to keep it working properly.

Liver support

Administering SAMe (S-Adenosylmethionine), which is found in Denamarin, has been shown to markedly increase liver levels of glutathione, 1, 2 an important compound for liver health formed when SAMe is metabolized. The SAMe in Denamarin has also been shown to help protect liver cells from cell death 3, 4 and may help cell repair and regeneration. 5

Denamarin also helps support your pet's liver through the administration of SILYBIN. SILYBIN is an active part of an extract from milk thistle, known as silymarin, and has been shown to support liver function by helping maintain a healthy oxidative balance.

While best known for supporting the liver in dogs and cats, research has shown that the S-Adenosylmethionine (SAMe) in Denamarin may help support cognitve function in dogs 6. Denamarin provides SAMe in a stabilized form to help with brain health and act as a neuroprotector. Denamarin also provides a bioavailable form of silybin which supports oxidative balance.

Denamarin has no known serious side-effects. Your veterinarian can evaluate the length of support needed through follow-up examinations, blood work, and/or other laboratory work. At home, watch for a reponse in your pet's attitude, appetite, and activity level.

Denamarin is available as enteric-coated tablets for dogs and cats and in tasty chewable tablets for dogs. Advanced technology in the exclusive NMXSS75® S-Adenosylmethionine found in the chewable formulation provides stability, eliminating the need for enteric coating or foil-on-foil blistering. The chewable tablets for dogs are tasty, single size and scored for easy administration. Additionally, the chewable tablets allow for quicker uptake of the SAMe and less variability between dogs when compared to enteric-coated tablets.

Denamarin is available from your veterinarian. Please consult your veterinarian to see if Denamarin is right for your pet.

A Denamarin Success Story

Denamarin for my Dachshund

"My beloved 13 year old dachshund had been acting very sluggish and tired for several months--I attributed it to the normal aging process. One day, I brought him to the vet after he had refused to move off of the couch and just lay there shaking for a few hours for no apparent reason. After a thorough examination, the vet determined that his liver enzymes were elevated and recommended Denamarin. Several months later, I am so happy to notice that his energy levels have not only returned, he is like a new dog. He has the same energy level he had when he was a younger dog. A follow up visit to the vet has confirmed that his liver enzyme levels have decreased and are close to the normal range. Thank you!"

FAQs

Denamarin Frequently Asked Questions

Liver Product
Selector

What product is right for my pet?

Liver Health Supplements Nutramax Laboratories Veterinary Sciences, Inc. Liver Health Supplements Denamarin Denamarin Denamarin Product Marin Plus Marin Plus Marin Plus Product Denosyl Denosyl Denosyl Product
Species
Species For Dogs
For Cats
Supplement Form
Supplement Form Enteric-coated Tablet
Chewable Tablet
Soft Chew
Active Ingredients
Active Ingredients
SAMe Increases levels of glutathione which is an important compound protecting liver health.
Silybin The silybin found in Denamarin and Marin Plus for dogs is complexed with phosphatidylcholine which has been shown to increase absorption 4x in dogs compared to standardized milk thistle extracts.
Vitamin E An antioxidant that has been shown to help protect liver function.
Zinc Supplementation may be beneficial in dogs with long-term decreased liver function as these dogs often have low liver zinc levels. Zinc participates in many enzymatic reactions within the body, and any deficiency may have harmful effects. Zinc is not in Marin for Cats as deficiencies have not been noted in cats.
Curcumin Curcumin has been shown to inhibit several mediators, supporting a healthy inflammatory response. It also helps increase production of glutathione, the liver's main antioxidant and “detoxifier” and protects against fibrotic changes in the liver.
Medium Chain Triglyceride (MCT) Oil In the liver, MCTs can be used for energy for metabolic reactions. MCTs can also help reduce fat deposition, which may occur in the liver secondary to compromise.
Possible Veterinarian Recommended Suggested Uses
Possible Veterinarian Recommended Suggested Uses For acute liver cases resulting in sharply elevated liver enzymes
Acetaminophen toxicity
For chronic liver cases
When using long term therapies with possible hepatotoxic agents
Possible Veterinarian Recommended Suggested Uses
Additional Suggested Uses When administration on an empty stomach is needed
Administration with food is needed
When zinc and/or Vitamin E may benefit
When a more economical choice is preferred
For brain health
Liver Health Supplements Nutramax Laboratories Veterinary Sciences, Inc. Liver Health Supplements Denamarin Denamarin Denamarin Product Marin Plus Marin Plus Marin Plus Product Denosyl Denosyl Denosyl Product

Check Plus Suggested to use combination of Denamarin AND Marin Plus for best results.